Hormones, Weight Regulation, and How New Medications Help
1. Why weight loss is hard: the body’s hormonal defense system When you lose weight, the body interprets it as a threat to survival and activates compensatory hormones to restore lost weight. Key players include: Result: After dieting, hunger increases, metabolism slows, and the body becomes more efficient at storing calories — making long-term weight maintenance difficult. 2. How […]
Weight Loss Medications vs Traditional Methods: A Comparison
1. Traditional approaches (diet, exercise, behavioral programs) 2. Wegovy (semaglutide 2.4 mg) 3. Mounjaro (tirzepatide) 4. Traditional weight-loss medications (older options) 5. Side-by-side effectiveness snapshot Approach Average weight loss Long-term maintenance Key notes Lifestyle only (diet + exercise + behavior) 5–10% Often partial regain within 2–5 years No drug risks Older drugs (e.g., orlistat) 3–10% Variable, modest […]
A Practical Guide to the New Weight-Loss Medications – comparing Wegovy with Mounjaro
Quick overview How do they work? Effectiveness – how much weight loss? Takeaway: Tirzepatide shows greater average weight loss than semaglutide. Cardiovascular outcomes Side effects and precautions Common to both: Specific notes: Contraindications (both): Personal/family history of medullary thyroid carcinoma (MTC) or MEN2. Caution with prior pancreatitis. Before surgery/anesthesia: GLP-1 drugs may delay gastric emptying—discuss with your medical team. Dosing (weekly injections, […]
